VOLUME I

Section I Theory: Physics 1

1 A Generic Thermal Model for Perfused Tissues 3
Devashish Shrivastava

2 Alternate Thermal Models to Predict in vivo Temperatures 15
Devashish Shrivastava

3 Thermal Effects of Blood Vessels 25
Devashish Shrivastava

4 Generating Blood Vasculature for Bioheat Computations 33
David Porter

5 Whole-Body Human Computational Models and the Effect of Clothing 53
Daniela Zavec Pavlinic and Eugene H.Wissler

6 Models of the Cardiovascular System 71
M. Keith Sharp

7 Lumped ParameterModeling of Human Respiratory System 119
Rachana Visaria

8 Inverse Heat Transfer for Biomedical Applications 133
Elaine P. Scott

9 Fundamentals of Propagation of Light in Tissue 153
Do-Hyun Kim

10 Ultrasound Propagation in Tissue 167
Joshua E. Soneson

11 ElectromagneticWaves and Fields in the Human Body in MRI 183
Jinfeng Tian

12 Electromagnetic Distribution in Tissue with Conductive Devices 203
John Nyenhuis

13 Techniques for Fast Computation 233
David Porter

14 Principles of TemperatureMeasurement with Temperature Probes in Bioheat Transfer Applications 261
Pradyumna Ghosh

15 Non-Invasive Thermometry with Magnetic Resonance Imaging 267
Henrik Odéen and Dennis L. Parker

16 Ultrasound Thermography: Principles, Methods, and Experimental Results 301
Emad S. Ebbini

17 Thermal Property Measurements 333
Jonathan W. Valvano

18 Measurement and Thermal Dependence of Biological Tissue Optical Properties 355
William C. Vogt, Jennifer K. Barton, Anant Agrawal and T. Joshua Pfefer

19 Measurement of Dielectric Properties of Tissue 379
Anand Gopinath

20 Micro- and Nanoscale Calorimetry for Biomedical Applications 393
Harishankar Natesan and John C. Bischof

VOLUME II

Section II Theory: Physiology 433

21 Cardiovascular and Metabolic Responses to Thermal Insults 435
Thad E.Wilson

22 Morphological and Physiological Considerations for the Modelling of Human Heat Loss 463
Nigel A.S. Taylor and Sean R. Notley

23 Adjustments in Thermoregulation during Radiofrequency Heating 501
Christopher J. Gordon

24 Burn: A Clinical Perspective 513
Mayank Singh and Surya Prakash

25 Response of the Thermoregulatory Systemto Toxic Chemicals 529
Christopher J. Gordon

26 Irreversible Tissue Thermal Alterations: Skin Burns, Thermal Damage and Cell Death 553
John Pearce

27 Models andMechanisms of Tissue Injury in Cryosurgery 591
Anthony T. Robilotto, John M. Baust, Robert G. Van Buskirk and John G. Baust

Section III Applications 619

28 In vivo Radiofrequency Heating in a 3T MRI Scanner 621
Jinfeng Tian and Devashish Shrivastava

29 Magnetic Nanoparticle Hyperthermia in Cancer Treatment: History, Mechanism, Imaging-Assisted Protocol Design, and Challenges 631
Alexander LeBrun and Liang Zhu

30 Modeling Combined Cryosurgery and Hyperthermia with Thermally Significant Blood Vessels 669
Gang Zhao, Fazil Panhwar and Zhongrong Chen

31 Cryoablation for the Treatment of Solid Cancers and Pain Management 687
Satish Ramadhyani

32 Effect of Blood Flow on MRI-Induced Heating near Stents 715
Devashish Shrivastava

33 Skin Burns 723
John P. Abraham, Brian D. Plourde, Lauren J. Vallez, Brittany B. Nelson-Cheeseman, John R. Stark, Ephraim M. Sparrow and JohnM. Gorman

34 Surface and Endovascular Cooling: Methods, Models, and Measurements 741
Thomas L. Merrill and Jennifer E.Mitchell

35 Estimation ofWind Chill Equivalent Temperatures (WCETs) 753
Avraham Shitzer

36 Temperature Postmortem: Theories, Models, and Measurements 773
Michael Hubig, Holger Muggenthaler, Senta Niederegger and Gita Mall

Index 809