Perioperative neurocognitive disorders are the most common and least recognized complications of anesthesia and surgery in older patients. This book represents the first unified source of information on this group of disorders, serving as a practical guide on diagnosis, pathophysiology and clinical recommendations. The book introduces new nomenclature that is recognized across medical specialties, tackles issues of informed consent and screening, interprets a plethora of scientific results from both animals and patients, and suggests mitigation strategies. In order to present and discuss essential knowledge and application in clinical practice as well as highlighting areas of controversy, this important book features expert contributions from the multidisciplinary field of perioperative care and cognitive disorders. It will appeal to the entire perioperative team as well as to neurologists, geriatricians, psychologists and researchers in the field.

The first book of its kind covering the perioperative neurocognitive disorders
Introduces a new, accessible nomenclature for these disorders, allowing patients, providers and scientists to start talking the same language
Organizes the topics into phenotype, pathophysiology, mechanisms and mitigation to facilitate a better understanding
Roderic G. Eckenhoff, University of Pennsylvania
Roderic G. Eckenhoff is an anesthesiologist and scientist at the University of Pennsylvania Perelman School of Medicine. He holds the Austin Lamont Chair in Anesthesiology and Critical Care and is Vice Chair for Research in that department. His primary research interest has been in the molecular pharmacology of general anesthetics, work that revealed effects on protein structure and function that should translate to neurodegenerative diseases and neuroinflammation.

Niccolò Terrando, Duke University, North Carolina
Niccolò Terrando is a neuroscientist at Duke University, North Carolina. His laboratory studies the pathogenesis of perioperative neurocognitive disorders, with emphasis on the mechanisms whereby surgery affects brain function and how regulation of neuro-immune processes can be targeted to develop safer mitigation strategies to prevent these common postoperative complications.