This text serves as a very useful clinical guide and realistic approach to the clinical management of melanoma. Primary care physicians, specialists from varying areas of medical practice and numerous other healthcare providers will find this text to be quite useful as a standard daily reference and use in the office setting. It provides a clear and concise source of information in order to make real-life, evidence-based decisions for all aspects of management for cutaneous melanoma. This book also provides the latest breakthroughs in melanoma research, ranging from recent discoveries in genomics and epigenetics, to newly identified genes that have been selectively targeted for the development of a personalized approach to treatment. All chapters are written by specialists and true experts within their respective fields, incorporating the latest scientific, clinical and evidence-based medicine for melanoma (and non-melanoma skin cancers). This up-to-date information can be easily applied and translated to the clinical setting for the melanoma patient.

Adam Riker
Professor of Surgery. Chief, Section of Surgical Oncology
Department of Surgery
Louisiana State University, School of Medicine
New Orleans, Louisiana 70112 USA
Contents

History of Melanoma.- Anatomy and Physiology of the Skin.- Melanoma Epidemiology and Prevention.- Methods of melanoma Detection.- Staging and Classification of Melanoma.- The Genetic Evolution of Melanoma.- Epigenetics in Melanoma.- Immunobiology of the Melanoma Microenvironment.- Dermoscopy of Melanocytic Lesions.- International Models of Melanoma Management (Australia).- Pigmented Lesions: Biopsy Methods and Emerging Noninvasive Imaging Techniques.- The Pathology of Melanoma.- Pediatric Melanoma and Atypical Melanocytic Neoplasms.- Melanoma in Pregnancy.- Mucosal Melanoma.- Uveal Melanoma.- Current Surgical Management of Primary Cutaneous Melanoma.- Mohs Surgery for Melanoma-in-Situ.- Surgical Management of Head and Neck Melanoma.- Management of Melanoma Locoregional Recurrence.- Reconstruction Options for Ear and Nose Melanoma.- Reconstruction Options for Lip, Cheek, Forehead and Scalp Melanoma.- Reconstructions Options for Trunk and Extremity Melanoma.- Sentinel Lymph Node Biopsy for Melanoma.- Operative Techniques for Melanoma.- Isolated Limb Infusion for Recurrent and Locally Metastatic Limb Melanoma.- Surgery for Stage IV Metastatic Melanoma.- Adjuvant Therapy of Melanoma.- Radiation Therapy for Melanoma.- Immuno-oncolytic Virotherapy for Melanoma.- Chemotherapy and Biochemotherapy for Melanoma.- Therapeutic Cancer Vaccines for Melanoma.- Adoptive Cell Therapy for Melanoma.- Current Immunotherapy of Melanoma.- Immune-Related Adverse Toxicities and Clinical Management.- Management of Non-Melanoma Skin Cancers: Basal Cell Carcinoma, Squamous Cell Carcinoma.- Management of Non-Melanoma Skin Cancers: Rare Subtypes.- Management of Non-Melanoma Skin Cancers: Merkel Cell Carcinoma.