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The Annual Update compiles reviews of the most recent developments in experimental and clinical intensive care and emergency medicine research and practice in one comprehensive reference book. The chapters are written by well recognized experts in these fields. The book is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
Prof. Vincent is Professor of intensive care at the University of Brussels, and intensivist in the Department of Intensive Care at Erasme University Hospital in Brussels. He is President of the World Federation of Societies of Intensive and Critical Care Medicine (WFSICCM) and a Past-President of the Belgian Society of Intensive Care Medicine (SIZ), the European Society of Intensive Care Medicine (ESICM), the European Shock Society (ESS), and the International Sepsis Forum (ISF). He is a member of the Royal Medical Academy of Belgium.Prof. Vincent has signed more than 900 original articles, some 400 book chapters and review articles, 1000 original abstracts, and has edited 102 books. He is co-editor of the Textbook of Critical Care (Elsevier Saunders) and the "Encyclopedia of Intensive Care Medicine" (Springer). He is editor-in-chief of "Critical Care", "Current Opinion in Critical Care", and "ICU Management & Practice" and member of the editorial boards of about 30 journals.
For 37 years, Prof. Vincent has been chairman of the International Symposium on Intensive Care and Emergency Medicine, the largest international meeting in this field, which gathers more than 6000 participants every year in Brussels.
He has received several awards, including the Distinguished Investigator Award of the Society of Critical Care Medicine and the College Medalist Award of the American College of Chest Physicians He is a recipient of the "Society Medal" (lifetime award) of the European Society of Intensive Care Medicine and has received the prestigious Belgian scientific award of the FRS-FNRS (Prix Scientifique Joseph Maisin-Sciences Biomedicales Cliniques). In recognition of these achievements, he was awarded the title of Baron by King Albert II of Belgium in 2013.
Contents Part I. Sepsis: underlying mechanisms.- Lipid mediators in the pathogenesis and resolution of sepsis and ARDS.- Immune paralysis in sepsis: recent insights and future development.- Persistent inflammation, immunosuppression and catabolism after severe injury or infection.- Part II. Antimicrobial issues.- Current trends in epidemiology and antimicrobial resistance in neonatal sepsis.- Prolonged infusion of beta-lactam antibiotics in critically ill patients: revisiting the evidence.- Colistin dosing in continuous renal replacement therapy.- Part III. Cardiovascular concerns.- Left ventricular diastolic dysfunction in the critically ill.- Management of intraoperative hypotension: prediction, prevention and personalization.- Vasodilatory shock In the intensive care unit: perils, pitfalls and therapeutic options.- Angiotensin in critical care.- Part IV. Cardiovascular resuscitation.- Making sense of early high-dose intravenous vitamin C in ischemia-reperfusion injury.- Optimal oxygen and carbon dioxide targets during and after resuscitated cardiac arrest.- Outcome after cardiopulmonary resuscitation.- Medico-economic evaluation of out-of-hospital cardiac arrest patient management.- Part V. Respiratory support.- A systematic review of the high flow nasal cannula for adult patients.- Role of tissue viscoelasticity in the pathogenesis of ventilator-induced lung injury.- Close down the lungs and keep them resting to minimize ventilator-induced lung injury.- Alveolar recruitment in patients with assisted ventilation: open up the lung in spontaneous breathing.- Diaphragm dysfunction during weaning from mechanical ventilation.- Part VI. Monitoring: new aspects.- Emerging technology platforms for optical molecular imaging and sensing at the alveolar level in the critically ill.- Contributors to differences between mixed and central venous oxygen saturation.- Bioelectrical impedance analysis in the critical care setting.- Part VII. Acute renal failure.- Acute kidney injury and microcirculatory shock.- Critical care ultrasonography and acute kidney injury.- Acute kidney injury risk prediction.- Risk stratification profile performance in predicting acute kidney injury in ICU patients.- Early detection of acute kidney injury after cardiac surgery - A solved problem?.- Biomarker-guided care bundles for acute kidney injury: the time has come.- Part VIII. Renal replacement therapy.- High cut-off membranes for continuous renal replacement therapy: review of human studies, prescription and clinical effects.- The role of intraoperative renal replacement therapy in liver transplantation.- Part IX. Fluid administration.- Effects of fluids on the macro and microcirculation.- Regulation of cardiac output and manipulation with fluids.- Assessment of fluid responsiveness in patients with intra-abdominal hypertension.- Assessment of fluid overload in critically ill patients: role of bioelectrical impedance analysis.- Part X. Coagulopathy and blood products.- Prothrombin complex concentrate: anticoagulation reversal and beyond.- Advances in mechanisms, diagnosis and treatment of coagulopathy and progression of hemorrhage after traumatic brain injury.- Blood transfusion in critically ill patients with traumatic brain injury.- Part XI. Acute cerebral concerns.- Systemic inflammation and cerebral dysfunction.- Opening a window to the injured brain: non-invasive neuromonitoring with quantitative pupillometry.- Brain ultrasound: how, why, when and where?.- Continuous EEG monitoring in adults in intensive care unit.- Respiratory management in patients with severe brain injury.- Part XII. Therapeutic issues.- Central alpha2-adrenoreceptor agonists in intensive care.- Rituximab-related severe toxicity.- Between dream and reality in nutritional therapy: how to fill the gap.- Part XIII. Moving the patient.-Interhospital transport during ECMO.- Early mobilization in intensive care: organization, communication and safety factors that influence translation into clinical practice.- Part XIV. The future.- The emerging role of the microbiota on the ICU.- In pursuit of precision medicine in the critically ill.- Future roles for xenon in emergency medicine and critical care.- Electronic health record research in critical care: the end of the randomized controlled trial?.- Using telemedicine in the ICU setting.- Index