The first edition of The Bethesda System for Reporting Thyroid Cytopathology was published in 2010 and has greatly influenced the practice of thyroid cytopathology. The terminology proposed and illustrated in this text has been widely adopted not only in the U.S. but also abroad. It has become an essential text for pathology trainees and practicing pathologists examining thyroid fine needle aspiration (FNA) specimens.
Since 2010, there have been a number of important advances in the management of patients with nodular thyroid disease and in the understanding of the biology of thyroid cancer. This new edition includes these advances that impact terminology for reporting thyroid cytopathology. In particular, it incorporates a discussion of the recently implemented and now widespread use of molecular testing of thyroid FNA samples, which has transformed the management of patients with nodular thyroid disease in the U.S.. In addition, this edition accommodates the recent changes to the classification of thyroid cancer, most notably the introduction of a new thyroid diagnosis, that of "non-invasive follicular tumor with papillary-like nuclear features (NIFTP)".
Thoroughly revised and updated, The Bethesda System for Reporting Thyroid Cytopathology, Second Edition will provide the reader with a unified approach to diagnosing and reporting thyroid FNA interpretations. It serves as a reference guide not just for pathologists, but also endocrinologists, surgeons, and radiologists

Table of contents (12 chapters)
Overview of Diagnostic Terminology and Reporting
Baloch, Zubair W. (et al.)
Pages 1-6
Nondiagnostic/Unsatisfactory
Crothers, Barbara A. (et al.)
Pages 7-18
Benign
Elsheikh, Tarik M. (et al.)
Pages 19-48
Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance
Krane, Jeffrey F. (et al.)
Pages 49-70
Follicular Neoplasm/Suspicious for a Follicular Neoplasm
Henry, Michael R. (et al.)
Pages 71-80
Follicular Neoplasm, Hürthle Cell (Oncocytic) Type/Suspicious for a Follicular Neoplasm, Hürthle Cell (Oncocytic) Type
Faquin, William C. (et al.)
Pages 81-100
Suspicious for Malignancy
VanderLaan, Paul A. (et al.)
Pages 101-118
Papillary Thyroid Carcinoma, Variants, and Related Tumors
Pusztaszeri, Marc P. (et al.)
Pages 119-156
Medullary Thyroid Carcinoma
Nishino, Michiya (et al.)
Pages 157-175
Poorly Differentiated Thyroid Carcinoma
Bongiovanni, Massimo (et al.)
Pages 177-188
Undifferentiated (Anaplastic) Carcinoma and Squamous Cell Carcinoma of the Thyroid
Staerkel, Gregg A. (et al.)
Pages 189-204
Metastatic Tumors, Lymphomas, and Rare Tumors of the Thyroid
Layfield, Lester J. (et al.)
Pages 205-230