A fundamental and respected resource book in critical care, The ICU Book, Fourth Edition, continues to provide the current and practical guidance that have made it the best-selling text in critical care. The text addresses both the medical and surgical aspects of critical care, delivering the guidance needed to ensure sound, safe, and effective treatment for patients in intensive care regardless of the specialty focus of the unit.
Problem-based approach teaches critical thinking and mirrors the decision-making process of the intensive care unit.
Expert perspectives from Dr. Marino help sharpen technique, minimize error, and improve outcomes.
Reader-friendly format makes essential information easy to locate and apply.
"Final Word" summaries at the conclusion of each chapter highlight salient points and improve retention of key concepts.

NEW to the Fourth Edition
Fully rewritten content (including eight new chapters plus a new Appendix on drug dosing) assures readers of only the most up-to-date and practical information available.
Full-color format emphasizes clinical anatomy and facilitates visual learning.
Companion website with fully searchable text also includes literature updates and commentaries by Dr. Marino helps readers stay current with the field's latest advances.

Section I: Vascular Access
1. Vascular Catheters
2. Central Venous Access
3. The Indwelling Vascular Catheter
Section II: Preventive Practices in the ICU
4. Occupational Exposures
5. Alimentary Prophylaxis
6. Venous Thromboembolism
Section III: Hemodynamic Monitoring
7. Arterial Blood Pressure
8. The Pulmonary Artery Catheter
9. Cardiovascular Performance
10. Systemic Oxygenation
Section IV: Disorders of Circulatory Flow
11. Hemorrhage and Hypovolemia
12. Colloid & Crystalloid Fluids
13. Acute Heart Failure(s)
14. Inflammatory Shock Syndromes
Section V: Cardiac Emergencies
15. Tachyarrhythmias
16. Acute Coronary Syndromes
17. Cardiac Arrest
Section VI: Blood Components
18. Erythrocyte Transfusions
19. Platelets & Plasma
Section VII: Blood Components
20. Hypoxia & Hypercapnia
21. Oximetry & Capnography
22. Oxygen Inhalation Therapy
23. Acute Respiratory Distress Syndrome
24. Asthma & COPD in the ICU
Section VIII: Mechanical Ventilation
25. Positive-Pressure Ventilation
26. Modes of Ventilatory Support
27. Specialized Ventilatory Support
28. The Ventilator-Dependent Patient
29. Ventilator-Associated Pneumonia
30. Discontinuing Mechanical Ventilation
Section IX: Acid-Base Disorders
31. Acid-Base Evaluations
32. Metabolic Acidosis
33. Metabolic Alkalosis
Section X: Renal & Electrolyte Disorders
34. Oliguria & Acute Kidney Injury
35. Sodium & Water Imbalance
36. Potassium
37. Magnesium
38. Calcium & Phosphorus
Section XI: The Abdomen and Pelvis
39. Pancreatitis & Liver Failure
40. Abdominal Sources of Sepsis
41. Urinary Tract Infection
Section XII: Disorders of Body Temperature
42. Thermoregulatory Disorders
43. Fever in the ICU
Section XIII: Nervous System Disorders
44. Disorders of Mentation
45. Disorders of Movement
46. Acute Stroke & Related Disorders
Section XIV: Nutrition & Metabolism
47. Nutritional Requirements
48. Enteral Nutrition
49. Parenteral Nutrition
50. Adrenal & Thyroid Dysfunction
Section XV: Common Drug Therapies in the ICU
51. Analgesia & Sedation
52. Antimicrobial Therapy
53. Vasoactive Drugs
Section XVI: Toxicologic Emergencies
54. Pharmaceutical Drug Overdose
55. Nonpharmaceutical Intoxications
Section XVII: Appendices
Appendix 1. Units and Conversions
Appendix 2. Selected Reference Ranges
Appendix 3. Measures of Test Performance
Appendix 4. Drug Dosing in Renal Failure