Once an uncommon clinical finding, the Chiari malformations are now frequently seen with the advent of more sophisticated imaging modalities. With more than one hundred years of experience with these entities, medicine currently has a much better understanding of the embryology and pathophysiology of the disorder. Long-term outcome studies are becoming more prevalent and patients are commonly operated on with generally favorable results. Comprehensive in design, the The Chiari Malformations focuses on the two most common forms of hindbrain herniation, the Chiari I and II malformations. Since the original description and classification of hindbrain hernias more than one hundred and twenty years ago, the Chiari malformations have revealed much of their pathophysiology and have become easily diagnosed radiologically. Indeed with the availability of MRI, more and more patients are being labeled with the diagnosis but without symptoms or appropriate symptoms. Timely and an invaluable addition to the literature, The Chiari Malformations thoroughly details the progress that has been made with our understanding of these conditions, their radiologic definition, details of operative intervention and prediction of outcome.

Table of contents Ch.1: Introduction and Classification of the Chiari Malformations:

Shane Tubbs, Jerry Oakes

Ch. 2: The Chiari Malformations: a Historical Context

Shane Tubbs, Jerry Oakes


Ch. 3: Embryology of the Craniocervical Junction and Posterior Cranial Fossa

Shane Tubbs, Mohammadali Shoja, Jerry Oakes


Ch. 4: Embryology and Pathophysiology of the Chiari I and II Malformations

Shane Tubbs, Mohammadali Shoja, Jerry Oakes

Ch.5: Surgical Anatomy of the Craniocervical Junction Relevant to Chiari Malformations

Shane Tubbs, Mohammadali Shoja, Jerry Oakes, Marios Loukas

Ch. 6: Epidemiology of the Chiari I Malformation

John D. Heiss

Ch. 7: Genetics of the Chiari I and II Malformations

Christina A. Markunas, Allison E. Ashley-Koch, Simon G. Gregory

Ch. 8: Pathology of Chiari I and II Malformations

Lucy B. Rorke-Adams

Ch. 9: Pathology of Syringomyelia Due to Chiari Malformations

Keith Harrison

Ch. 10: Associated Disorders of Chiari Type I Malformations

Shane Tubbs, Jerry Oakes

Ch. 11: Chiari-like Malformation in Dogs

Dominic J. Marino, Curtis W. Dewey

Ch. 12: Radiology of the Chiari Malformations

Jim Barkovich, Abby E. Deans

Ch. 13: Research on the Pathophysiology of Chiari I-Related Symptoms and Syringomyelia, with Emphasis on Dynamic MRI Techniques

Carolina Sandoval-Garcia, Bermans J. Iskandar

Ch. 14: Associated Bony Malformations and Instability in the Chiari I Malformation

Arnold H. Menezes

Ch. 15: Non-Hindbrain Related Syringomyelia

Jorg Kleklamp

Ch. 16: Secondary Interventions for Chiari I Malformation

Jorg Kleklamp

Ch. 17: Scoliosis and Chiari I Malformations

Heather Spader, Douglas L. Brockmeyer

Ch. 18: Natural History of Chiari Malformations

Cormac O. Maher

Ch. 19: Newer Subsets: Chiari 0 and Chiari 1.5 Malformations

Nitin R. Mariwalla, William R. Boydston, Joshua J. Chem

Ch. 20: Clinical Presentation of Pediatric Chiari I Malformations

Curtis Rozzelle

Ch. 21: Clinical Presentation of the Adult Chiari I Malformation

Ulrich Batzdorf

Ch. 22: Unusual Presentations of the Chiari I Malformation

Christopher M. Bonfield, Elizabeth Tyler-Kabara


Ch. 23: Association Between Fibromyalgia, Chronic Fatigue, and the Chiari I Malformation

Richard Ellenbogen, David Bauer

Ch. 24: The Chiari Malformations and Hydrocephalus

James M. Johnston, John C. Wellons III

Ch. 25: Symptoms of the Chiari II Malformation

Jeffrey P. Blount

Ch. 26: Treatment of the Adult Chiari I Malformation

John D. Heiss, Edward H. Oldfield

Ch. 27: Treatment of the Pediatric Chiari I Malformation

Jerry Oakes

Ch. 28: Treatment of the Chiari II Malformation

Jerry Oakes

Ch. 29: Complications of Chiari Surgery

Tyler Auschwitz, Frederick Boop

Ch. 30: Outcomes for the Surgical Management of Chiari I and Chiari II Malformations

Nathan J. Ranalli, David D. Limbrick Jr., Tae Sung Park

Ch. 31: A Multidisciplinary Clinic for the Management of Chiari IMalformations

Leon S. Dure, Jerry Oakes, Chevis N. Shannon, Camille Broome, Curtis Rozzelle, Tony McGrath

Ch. 32: Chiari Malformations: a Patient's Guide

Nadine Bradley, Haley Vance

Ch. 33: Conclusions

Shane Tubbs, Jerry Oakes