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Thrombosis and Hemorrhage

294.01
279.31
Now in its Third Edition, this authoritative text continues to provide a comprehensive and systematic review of the biology, pathobiology, and clinical disorders of the hemostatic system. Its unique organization of the basic sciences coupled with clinical sections yields a user-friendly integrated text, and a reference tool that meets the needs of diverse investigators and clinicians of contemporary medicine for understanding the hemostatic system. New chapter topics covered in this edition include angiogenesis and vasculogenesis; hemorrhagic complications of antithrombotic therapy; interactions of coagulation and fibrinolytic proteins with the vessel wall; and less common thrombotic disorders.

Contents

SECTION 1 COAGULATION AND FIBRINOLYSIS
1. Coagulation Cascade: An Overview
2. Molecular Genetics of Blood Coagulation
3. Regulation of Coagulation
4. Tissue Factor Pathway of Coagulation
5. Fibrin Formation and Stabilization
6. Fibrinolysis and its Regulation

SECTION 2 PLATELETS
7. Regulation of Megakaryopoiesis
8. Platelet Morphology
9. Platelet Membranes and Receptors
10. Mechanisms of Platelet Activation and Signal Transduction

SECTION 3 VESSEL WALL
11. Overview of the Endothelium
12. Angiogenesis and Vasculogenesis
13. Vascular Response to Injury
14. von Willebrand Factor
15. Interactions of Coagulation and Fibrinolytic Proteins with the Vessel Wall
16. Endothelium-derived Vasoactive Factors
17. Rheology

SECTION 4 CLINICAL APPROACH TO BLEEDING AND THROMBOSIS
18. Approach to Bleeding
19. Approach to Thrombosis
20. Assessment of Arterial and Venous Thrombosis
21. Laboratory Methods in Hemostasis

SECTION 5 QUANTITATIVE PLATELET DISORDERS
22. Thrombotic Microangiopathies
23. Alloimmune Thrombocytopenias
24. Drug-induced Thrombocytopenias
25. Immune Thrombocytopenic Purpura
26. Thrombocytosis

SECTION 6 QUALITATIVE PLATELET DISORDERS
27. Congenial Disorders of Platelet Function
28. Acquired Disorders of Platelet Function

SECTION 7 DISORDERS OF COAGULATION FACTORS AND FIBRINOLYSIS
29. von Willebrand Disease
30. Hemophilia-Factor VIII Deficiency
31. Other Coagulation Factor Deficiencies
32. Factor VIII and Other Coagulation Factor Inhibitors
33. Antiphospholipid Syndrome, Lupus, Anticoagulants, and Antiphospholipid Antibodies

SECTION 8 THROMBOTIC DISORDERS
34. Relationship Between Thrombosis and Atherosclerosis
35. Inherited and Acquired Hypercoagulable States
36. Endotheliopathies

SECTION 9 OTHER DISORDERS OF HEMOSTASIS
37. Less Common Thrombotic Disorders
38. Vascular Purpura and Diseases of Blood Vessels
39. Disseminated Intravascular Coagulation
40. Coagulopathy of Liver Failure and Vitamin K Deficiency
41. Maternal Hemostasis: Coagulation Problems of Pregnancy
42. Hemorrhage, Thrombosis, and Antithrombotic Therapy in Children
43. Interaction of Blood and Artificial Surfaces

SECTION 10 MANAGEMENT OF BLEEDING
44. Platelet Transfusion Therapy
45. Plasma and Component Therapy
46. Non-transfusional Modalities

SECTION 11 MANAGEMENT OF THROMBOSIS
47. Pharmacology of Antiplatelet Agents
48. Pharmacology of Heparin and Oral Anticoagulants
49. Pharmacology of Thrombolytic Agents
50. New Antithrombotic Strategies
51. Hemorrhagic Complications of Antithrombotic Therapy
52. Antithrombotic Interventions in Cerebrovascular Disease
53. Antithrombotic Therapy in Cardiovascular Disease
54. Antithrombotic Therapy in Peripheral Vascular Disease
55. Anticoagulants in Atrial Fibrillation
56. Prevention and Treatment of Venous Thromboembolic Disease
57. Gene Therapy of Thrombotic and Hemorrhagic Disorders

ISBN
978-0-7817-3066-2
EAN
9780781730662
Editor
Lippincott Williams & Wilkins
Stock
NO
Idioma
Inglés
Nivel
Profesional
Formato
Encuadernado
Tapa Dura
Páginas
1170
Largo
-
Ancho
-
Peso
1700
Edición
Fecha de edición
01-10-2002
Año de edición
2002
Nº de ediciones
3
Colección
-
Nº de colección
-