KEY FEATURES:
Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design and other important recent advances in the field
Provides high-quality content in a comprehensive manner, including contributions from international authors to illustrate the global nature of medicinal chemistry and drug development research
Offers a thorough look at the daily issues facing pharmaceutical researchers and chemists


ANCILLARIES / TEACHING AIDS:
Incorporates extensive color figures, case studies, and practical examples throughout the book to help users gain a further understanding of key concepts
An image bank is available for instructors


TABLE OF CONTENTS:
Section 1 General Aspects of Medicinal Chemistry
Section 2 Lead Compound Discovery Strategies
Section 3 Primary Exploration of Structure-Activity Relationships
Section 4 Substituents and Functions: Qualitative and Quantitative Aspects of Structure-Activity Relationships
Section 5 Spatial Organization, Receptor Mapping and Molecular Modeling
Section 6 Chemical Modifications Influencing the Pharmacokinetic Properties
Section 7 Pharmaceutical and Chemical Means to Solubility and Formulation Problems