Pharmacology and Physiology in Anesthetic Practice is a comprehensive review of how anesthetic drugs work in the human body. This text has long been required reading for anesthesia residents and student nurse anesthetists. This title provides foundational content in the field of anesthesiology. Understanding and applying the concepts explained in this text are crucial to competence as an anesthesiologist.

Key Features:
Comprehensive clinical review of a difficult and crucial subject
Physiologic and pharmacological concepts are integrated in this edition rather than separated as in previous editions.
New editors Steve Shafer and James Rathmell are leading lights in the anesthesiology and pain medicine communities.
Whats New:
Full color throughout the fifth edition & all new art
Physiology and pharmacology are integrated rather than separated in the Table of Contents.
New chapter: Drug Delivery Systems, Drugs with anesthetic interactions, and Pharmacogenomics
Extensively updated Table of Contents

I. Basic Principles of Physiology and Pharmacology
1. Basic Principles of Physiology
Flood/Shafer,
2. Basic Principles of Pharmacology
Flood/Shafer,

II. Neurologic System
3. Neurophysiology
Flood/Shafer,
4. Inhaled Anesthetics
Flood/Shafer
5. Intravenous Sedatives and Hypnotics
Rosow
6. Pain physiology
Naguib
7. Opioid Agonists and Antagonists
Naguib.
8. Centrally acting non-opioid analgesics
Naguib
9. Peripherally acting analgesics
Naguib
10. Local Anesthetics
Naguib
11. Neuromuscular Physiology
Naguib
12. Neuromuscular Blocking Drugs and Reversal Agents
Naguib
13. Other neurologically active drugs
Flood

III. Circulatory System
14. Circulatory physiology
Teresa Mulaikal
15. Cardiac Physiology
Goswami/Kachulis
16. Renal physiology
Shanewise/J. Hastie
17. Intravenous Fluid Therapy
Spellman
18. Sympathomimetics
Heath/Lo
19. Sympatholytics
Miller
20. Vasodilators
Ramsay/Peatross
21. Antiarrhythmic
Ramsay/Anast
22. Diuretics
M. Hastie
23. Lipid Lowering Drugs
Smith/Shanewise

IV. Pulmonary System
24. Gas Exchange
Slinger
25. Bronchodilators
Slinger
26. Treatment of acid/base disorders
Slinger

V. Blood and Hemostasis
27. The physiology of hemostasis
Levy
28. Blood products as drugs and blood components
Levy
29. Procoagulants
Levy
30. Anticoagulants
Levy
31. Physiology and management of massive transfusion
Levy

VI. Gastrointestinal System and Metabolism
32. Gastrointestinal physiology
Murray
33. Metabolism
Murray
34. Antiemetics and Antacids
Murray
35. GI Motility drugs
Murray
36. Nutrition
Murray

VII. Endocrine System
37. Normal Endocrine Function
Moitra
38. Drugs that alter glucose regulation
Moitra
39. Drugs for the treatment of hypothyroid and hyperthyroidism
Moitra
40. Other Endocrine Drugs
Moitra

VIII. Miscellaneous
41. Antimicrobials
Shafer
42. Chemotherapeutic Drugs
Rathmell
43. Drugs for Psychopharmacology
Flood/Kwok
44. Antiseptics and Disinfectants
Rathmell

IX. Special Populations
45. Physiology and Pharmacology of the Newborn
Flood
46. Physiology and Pharmacology of the Parturient and Fetus
Flood
47. Physiology and Pharmacology of the Elderly
Shafer
48. Physiology and Pharmacology of Resuscitation
Murray