Worldwide, undergraduate medical curricula are moving towards integration of basic medical and clinical sciences to enhance student understanding of how the basic sciences underpin clinical medicine. Recent rapid progress made in the understanding of cellular mechanisms and genomics, together with developments in technical clinical procedures, means that the amount of factual knowledge required for the effective practice of medicine can be overwhelming for the undergraduate. Understanding and synthesis of this knowledge is essential for effective application to the practice of clinical medicine.

The team of clinical and scientific experts on this book integrates information from the diverse branches of medical science (such as cellular biochemistry, anatomy, physiology and genetics) with clinical examples to illustrate how dysfunction leads to disease. This book will give students of medicine a strong grounding in the basic sciences and how they inform clinical practice and medical understanding.KEY FEATURES

First textbook of its kind, designed to complement Kumar and Clark's Clinical Medicine by covering the basic sciences in a clinical context

Reflects undergraduate medical curricula changes, particularly, in the UK which have significantly reduced the amount of time students spend learning the basics sciences

Mirrors the current integrated approach to teaching the basic sciences (anatomy, physiology, biochemistry, pharmacology, general pathology) and provides all the student needs to know about these subjects in one textbook

Perfect introductory text for graduate medical students without a science background

Presentation, layout and design a mirror of Kumar and Clark's Clinical Medicine

TABLE OF CONTENTS

Introduction and homeostasis Jeannette Naish
Biochemistry and cell biology Marek Dominiczak
Energy metabolism Mark Holness, Mary Sugden and Jeannette Naish
Pharmacology Walter Wieczorek and Jeannette Naish
Human genetics Denise Syndercombe Court and David P Kelsell
Pathology and immunology Denise Syndercombe Court, Paola Domizio and Armine Sefton
Epidemiology: science for the art of medicine Jeannette Naish and Denise Syndercombe Court
The nervous system Brian Pentland
Bone, muscle, skin and connective tissue Lesley Robson and Denise Syndercombe Court
Endocrinology Joy Hinson and Peter Raven
The cardiovascular system Andrew Archbold and Jeannette Naish
Haematology Drew Provan, Adrian C Newland and Denise Syndercombe Court
The respiratory system Gavin Donaldson
The renal system Girish Namagondlu and Alistair Chesser
The alimentary system John Wilkinson
Diet and nutrition Amrutha Ramu, Penny Neild and Jeannette Naish